International Workshop on Gene Signalling Pathway Analysis and Representation

Fri 14th November, Centro Studi Nazionale CISL, Florence, Italy

UnifiDc-TheraLeaf

[Overview] [Workshop Description] [Topics of interest] [Venue and format] [Program] [Types of contributions]
[Deadlines, Registration and Paper Submission] [Instructions] [Chairs] [Program committee] [Info]

In cooperation with

DC-Thera: Dendritic Cell for Novel Immunotherapies, European Commission Network of Excellence
University of Florence, Italy
University of Rennes 1, France
Wayne State University, USA

Overview

The workshop focuses on the representation of signalling pathways and its application to -omics data analysis. It is held in conjunction with I-ATLAS: International Workshop on Gene Signalling Pathway Analysis and Representation for the Dendritic Cell. It will have a public of experts in the field and potential users, and will propose keynotes, selected talks and a poster session.

Workshop Description

Functional evaluation of -omics data is rising its importance as the volume and types of quantitative information on biological systems is increasing.
The use of pathway information in the interpretation of -omics data promises to overcome the problems arising from structural data noise and incomplete knowledge of biological systems.
This workshop aims at exploring the issues related to the representation of signalling pathways, and their application in the interpretation of functional genomics data.
It will have an applied focus, with a public consisting of experts in the field and potential users, and it is held in conjunction with I-ATLAS: International Workshop on Gene Signalling Pathway Analysis and Representation for immuno-genomics.
We will present DC-ATLAS, a highly curated database of pathways of the dendritic cell, structured in a way to facilitate access to knowledge on biological mechanisms at the molecular level using representations that capture the hierarchical structure of signalling from receptors to effectors.
The workshop will draw attention to issues related to pathway representations and ontologies, to statistical methods for the integration of pathway knowledge into data analysis, and to the visualization of pathway information.

Topics of Interest

The workshop focuses on the representation of signalling pathways and their use in -omics data interpretation. Topics of interest include, but are not limited to:

Workshop Venue and Format

Location: Centro Studi Nazionale CISL, Via della Piazzola 71, Florence, Italy
How to get Centro Studi Nazionale CISL:

BY CAR
Leave the highway at the exit of FIRENZE SUD. Follow the indications to Fiesole up to San Domenico. Via della Piazzola is on the left side, just after the "Camerata" Hospital. The parking of the Study Center is accessible at the n.69/A.

BY TRAIN
From the railway Station of Santa Maria Novella take the bus n. 7 till the bus stop of "Ospedale di Camerata" (Camerata's Hospital). Behind the hospital is via della Piazzola, after about 300 meters is situated the Study Center.

BY AIRPLANE
A fast connection with the Study Center is possible only using a Taxi. The journey, lasting about 20 minutes, will cost about 15-20 Euros. There are connections with the central railway station (Santa Maria Novella) from where is possible to take the bus n.7, but you will need at least 1 hour to go through the whole journey.

GOOGLE MAPS

Centro Studi Nazionale CISL Website

Date: 14th Nov. 2008

Program

Session: Statistical methods to assess enrichment in cellular functions
9.00-9.20 Duccio Cavalieri: Introduction
9.20-10.00 Keynote: Sorin Draghici, A systems biology approach for pathway level analysis
10.00-10.40 Luca Beltrame: EuGene - a bioinformatic method to query microarray databases using a pathway based logic
10.40-11.00 Coffee Break
Session: Cross-species meta-analysis and network reconstruction
11.00-11.40 Keynote: Chiara Romualdi, Statistical approaches to the meta-analysis of microarray data
11.40-12.20 Keynote: Misha Kapushesky, A meta-analytical approach for analyzing condition-specificity of expression in signalling pathways
12.20-12.45 Round Table and Discussion
12.45-14.00 Lunch Break
Session: Graphical representation and ontologies for networks and pathways
14.00-14.40 Keynote: Chris Evelo, WikiPathways and PathVisio
14.40-15.20

Keynote: Emek Demir, Towards a comprehensive map of cellular signaling: Current State and Challenges
15.20-16.00 Keynote: Gabriella Rustici, Reconstructing the Fission Yeast cell cycle gene regulatory network
16.00-16.20 Discussion
16.20-16.40 Coffee Break
16.40-17.00 Selected talk: Antonella Travaglione, Elisabetta Marras, Gautam Chaurasia, Matthias Futschik, Enrico Capobianco: Inferring modularity from human protein interactome classes
17.00-17.30 Michaela Guendel, The DC-THERA Directory: A knowledge management system to support collaboration on dendritic cell and immunology research
17.30-18.00 Conclusions

Types of contributions

The following possible original contributions are sought:
Accepted oral communications and posters will be included in the abstract's book distributed to the participants.
We will seek publication of extended extracts of selected papers in a prestigious journal.

Deadlines

Registration closes: November 12th Deadline for submitting papers: November 7th

REGISTRATION AND PAPER SUBMISSION

Instructions

Submission will be managed through EasyChair.

- Submissions for oral communications should be between 5 and 7 pages (A4, 12pt, single spacing)
- Poster submissions should be between 2 and 4 pages

We will pursue publication of extended extracts of selected papers in a high-quality journal.

Workshop chairs

Duccio Cavalieri, University of Florence, Italy
Sorin Draghici, Wayne State University, USA
Andrea Splendiani, University of Rennes 1, France

Program Committee

Duccio Cavalieri, University of Florence, Italy
Sorin Draghici, Wayne State University, USA
Andrea Splendiani, University of Rennes 1, France
info: info@i-atlas.org